Pipeline
Publications
Basile LA, Ellefson D, Gluzman-Poltorak Z, Junes-Gill K, Mar V, Mendonca S, Miller JD, Tom J, Trinh A, Gallaher TK. HemaMax™, a recombinant human interleukin-12, is a potent mitigator of acute radiation injury in mice and non-human primates. PLoS One. 2012;7(2):e30434. doi: 10.1371/journal.pone.0030434. Epub 2012 Feb 24. PMID: 22383962
Basile LA, Gallaher TK, Shibata D, Miller JD, Douer D. Multilineage hematopoietic recovery with concomitant antitumor effects using low dose Interleukin-12 in myelosuppressed tumor-bearing mice. J Transl Med. 2008 May 19;6:26. PMID: 18489769
Gallaher T, Basile L, Gluzman-Poltorak Z, Lawrence C, Tom J, Gokhale M, Vainstein V. Neumedicines Inc., Pasadena, CA. HemaMax™ Development as a Frontline, Single Dose Radiation MedicalCountermeasure. Global Conference on Radiation Topics; 2013 May 13-16; Munich, Germany.
Gallaher T, Basile L, Gluzman-Poltorak Z, Lawrence C, Tom J, Gokhale M, Vainstein V, Ellefson D. Neumedicines Inc., Pasadena, CA. HemaMax™ Simultaneously Enhances Near-Term Survival and Long-TermRecovery from Lethal Total Body Irradiation. Global Conference on Radiation Topics; 2013 May 13-16; Munich, Germany.
Ellefson D, Gallaher T, Gluzman-Poltorak Z, Mendonca S, Miller J, Basile L. Neumedicines Inc., Pasadena, CA. Mitigation of Acute Radiation Injury in Non-Human Primates and Mice by HemaMax™ (Recombinant Human Interleukin-12). Poster session presented at: 58th Annual Meeting of the Radiation Research Society; 2012 Sept 30 - Oct 3; San Juan, Puerto Rico.
Gluzman-Poltorak Z, Lu S, Trinh A, Bentsi-Barnes K, Lawrence C, Ellefson D, Tom J, Gallaher T, Basile L. Neumedicines Inc., Pasadena, CA. HemaMax™ (rHuIL-12): Pharmacokinetics and Pharmacodynamics. Poster session presented at: 58th Annual Meeting of the Radiation Research Society; 2012 Sept 30 - Oct 3; San Juan, Puerto Rico.
Trinh AT, Ball BG, Weber E, Gallaher TK, Gluzman-Poltorak Z, Anderson F, Basile LA. Retroviral vectors encoding ADA regulatory locus control region provide enhanced T-cell-specific transgene expression. Genet Vaccines Ther. 2009 Dec 30;7:13. PMID: 20042112
Junes-Gill KS, Gallaher TK, Gluzman-Poltorak Z, Miller JD, Wheeler CJ, Fan X, Basile LA. hHSS1: a novel secreted factor and suppressor of glioma growth located at chromosome 19q13.33. J Neurooncol. 2011 Apr;102(2):197-211. Epub 2010 Jul 31. PMID: 20680400